Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4342913 | 0.81 | APEX1 (0.36) | NPC1RAB9A | |
| SCHEMBL5671293 | 0.76 | NPC1 (0.37) | MAOAMAOBNPC1RAB9A | |
| Ether SCHEMBL16934634 | 0.75 | NPC1 (0.33) | NPC1RAB9A | |
| SCHEMBL28498007 | 0.75 | NPC1 (0.31) | NPC1RAB9A | |
| Methane SCHEMBL28000918 | 0.74 | NPC1 (0.36) | MAOAMAOBNPC1RAB9A | |
| SCHEMBL29803996 | 0.73 | NPC1 (0.33) | NPC1RAB9A | |
| SCHEMBL29170920 | 0.73 | NPC1 (0.42) | MAOAMAOBKDM1ANPC1RAB9A | |
| SCHEMBL29234913 | 0.71 | NPC1 (0.31) | NPC1RAB9A | |
| SCHEMBL5067245 | 0.71 | HDAC1 (0.35) | NPC1RAB9A | |
| SCHEMBL27932882 | 0.71 | MAOB (0.36) | MAOAMAOBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713514-B1 | SUCH AS 2-(BENZYLAMINO)-3-(4-(N-(3-PHENYLPROPYL)CARBAMOYL)-PHENYL)PROPANOIC ACID | LEXICON PHARMACEUTICALS, INC. | 2004-03-30 | — | — | US | disclosed |