Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.54 |
| ▸ | TGM2 | P21980 | 2/20 | 0.48 |
| ▸ | F13A1 | P00488 | 1/20 | 0.48 |
| ▸ | TGM1 | P22735 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6863673 | 0.86 | EPHX2 (0.44) | EPHX2KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL12004620 | 0.86 | EPHX2 (0.44) | EPHX2KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL12004619 | 0.86 | EPHX2 (0.44) | EPHX2KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL2320339 | 0.73 | EPHX2 (0.56) | EPHX2PTPN1ALDH1A1HPGDKMT2A | |
| SCHEMBL31315635 | 0.70 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL18980903 | 0.70 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL12005312 | 0.70 | USP30 (0.59) | EPHX2KMT2ANPC1RAB9ANAMPT | |
| SCHEMBL6863459 | 0.70 | USP30 (0.59) | EPHX2KMT2ANPC1RAB9ANAMPT | |
| SCHEMBL12005313 | 0.70 | USP30 (0.59) | EPHX2KMT2ANPC1RAB9ANAMPT | |
| SCHEMBL19000801 | 0.70 | EPHX2 (0.69) | EPHX2ALDH1A1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011032291-A1 | SELECTIVE CALCIUM CHANNEL MODULATORS | ZALICUS PHARMACEUTICALS LTD . (CA) | 2011-03-24 | — | — | WO | disclosed |