Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17960822 | 0.98 | TSHR (0.42) | TSHRPRKCAFAAHTRPV1THRB | |
| SCHEMBL1797486 | 0.95 | TSHR (0.44) | TSHRPRKCAFAAHTRPV1THRB | |
| SCHEMBL5606129 | 0.95 | TSHR (0.44) | TSHRPRKCAFAAHTRPV1THRB | |
| SCHEMBL15618662 | 0.95 | TSHR (0.44) | TSHRPRKCAFAAHTRPV1THRB | |
| SCHEMBL21300 | 0.95 | TSHR (0.44) | TSHRPRKCAFAAHTRPV1THRB | |
| SCHEMBL14915686 | 0.95 | TSHR (0.44) | TSHRPRKCAFAAHTRPV1THRB | |
| SCHEMBL353470 | 0.95 | TSHR (0.44) | TSHRPRKCAFAAHTRPV1THRB | |
| SCHEMBL15618384 | 0.95 | TSHR (0.44) | TSHRPRKCAFAAHTRPV1THRB | |
| SCHEMBL258172 | 0.93 | — | — | |
| SCHEMBL40358 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392740-A2 | PROCESS FOR THE PREPARATION OF ETHYLENE POLYMERS WITH A BIS-AMIDO TITANIUM COMPOUND | Basell Polyolefine GmbH (DE) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002024769-A2 | PROCESS FOR THE PREPARATION OF ETHYLENE POLYMERS WITH A BIS-AMIDO TITANIUM COMPOUND | BASELL TECHNOLOGY COMPANY B.V. (IT) | 2002-03-28 | — | — | WO | disclosed |