SCHEMBL6864115

SCHEMBL6864115

C[C@@](O)(C=O)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6827267 1.00
SCHEMBL14041824 1.00
SCHEMBL28263075 0.81
SCHEMBL7314158 0.73
SCHEMBL15142351 0.73
SCHEMBL7314148 0.73
SCHEMBL27744411 0.71
Acetaldehyde SCHEMBL28166925 0.69
SCHEMBL8665784 0.69
SCHEMBL436329 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008009710-A1 PROCESS FOR THE PRODUCTION OF FLUORINE CONTAINING ALPHA-HYDROXY CARBOXYLIC ACIDS SOLVAY FLUOR GMBH (DE) 2008-01-24 WO disclosed
EP-1881077-A1 Process for the production of fluorine containing a-hydroxy carboxylic acids Solvay Organics GmbH (DE) 2008-01-23 EP disclosed
US-20040058425-A1 Crystal structure PFIZER INC. 2004-03-25 US disclosed
EP-1247860-A1 Crystal structure of pyruvate dehydrogenase kinase 2 (PDHK-2) and use thereof in methods for identifying and designing new ligands Pfizer Limited (GB) 2002-10-09 EP disclosed