Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 0.76 |
| ▸ | FLT1 | P17948 | 11/20 | 0.76 |
| ▸ | FLT4 | P35916 | 11/20 | 0.76 |
| ▸ | KIT | P10721 | 1/20 | 0.76 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5205783 | 0.92 | KDR (0.73) | KDRFLT1FLT4KITPDGFRA | |
| SCHEMBL5205787 | 0.91 | KDR (0.83) | KDRFLT1FLT4KITPDGFRA | |
| Krn-633 SCHEMBL29356072 | 0.86 | KDR (1.00) | KDRFLT1FLT4KITPDGFRA | |
| Krn-633 SCHEMBL1249684 | 0.86 | KDR (1.00) | KDRFLT1FLT4KITPDGFRA | |
| Krn-633 SCHEMBL29375090 | 0.86 | KDR (1.00) | KDRFLT1FLT4KITPDGFRA | |
| SCHEMBL5207815 | 0.85 | KDR (0.90) | KDRFLT1FLT4KITPDGFRA | |
| SCHEMBL5205625 | 0.84 | KDR (0.86) | KDRFLT1FLT4KITPDGFRA | |
| SCHEMBL5202078 | 0.84 | KDR (0.75) | KDRFLT1FLT4KITPDGFRA | |
| SCHEMBL5206267 | 0.84 | KDR (0.88) | KDRFLT1FLT4KITPDGFRA | |
| SCHEMBL5205807 | 0.83 | KDR (0.86) | KDRFLT1FLT4KITPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6797823-B1 | Quinoline derivatives and quinazoline derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 2004-09-28 | — | — | US | disclosed |