Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7018973 | 0.75 | HDAC3 (0.73) | HDAC3HDAC4HDAC1HDAC6ERN1 | |
| SCHEMBL6733518 | 0.69 | HDAC3 (0.47) | HDAC3HDAC4HDAC1HDAC6ERN1 | |
| SCHEMBL3253491 | 0.69 | HDAC3 (0.65) | HDAC3HDAC4HDAC1HDAC6ERN1 | |
| SCHEMBL5068414 | 0.69 | HDAC3 (0.65) | HDAC3HDAC4HDAC1HDAC6L3MBTL1 | |
| SCHEMBL12514085 | 0.68 | HDAC3 (0.59) | HDAC3HDAC4HDAC1HDAC6ERN1 | |
| SCHEMBL7421051 | 0.68 | HDAC3 (0.63) | HDAC3HDAC4HDAC1HDAC6ERN1 | |
| SCHEMBL2659566 | 0.67 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC6L3MBTL1 | |
| SCHEMBL3333355 | 0.67 | HDAC3 (0.58) | HDAC3HDAC4HDAC1HDAC6ERN1 | |
| SCHEMBL2296183 | 0.67 | HDAC6 (1.00) | HDAC3HDAC4HDAC1HDAC6ALDH1A1 | |
| SCHEMBL24035294 | 0.67 | HDAC3 (0.61) | HDAC3HDAC4HDAC1HDAC6ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409464-A1 | OXAZOLIDINONE DERIVATIVES AS POTENTIAL ANTIMICROBIALS | RANBAXY LABORATORIES, LTD. (IN) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003008389-A1 | OXAZOLIDINONE DERIVATIVES AS POTENTIAL ANTIMICROBIALS | RANBAXY LABORATORIES LIMITED (IN) | 2003-01-30 | — | — | WO | disclosed |