Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | RET | P07949 | 2/20 | 0.52 |
| ▸ | KIF5B | P33176 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | CCDC6 | Q16204 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 5/20 | 0.50 |
| ▸ | TEK | Q02763 | 3/20 | 0.50 |
| ▸ | LCK | P06239 | 3/20 | 0.50 |
| ▸ | HCK | P08631 | 1/20 | 0.50 |
| ▸ | RIPK2 | O43353 | 4/20 | 0.49 |
| ▸ | NEK7 | Q8TDX7 | 3/20 | 0.49 |
| ▸ | EIF2AK3 | Q9NZJ5 | 3/20 | 0.48 |
| ▸ | ABL1 | P00519 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | ABL2 | P42684 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867037 | 0.97 | SRC (0.53) | KDRRETKIF5BKCNH2CCDC6 | |
| SCHEMBL6461270 | 0.93 | RET (0.53) | KDRRETKIF5BKCNH2CCDC6 | |
| SCHEMBL6462768 | 0.91 | RET (0.54) | KDRRETKIF5BKCNH2CCDC6 | |
| SCHEMBL6465583 | 0.87 | RIPK2 (0.47) | KDRRETKIF5BKCNH2CCDC6 | |
| SCHEMBL6865257 | 0.87 | SRC (0.63) | KDRRETKIF5BKCNH2CCDC6 | |
| SCHEMBL6460851 | 0.87 | RIPK2 (0.60) | KDRRETKIF5BKCNH2CCDC6 | |
| SCHEMBL6460272 | 0.85 | SRC (0.61) | KDRRETKIF5BKCNH2CCDC6 | |
| SCHEMBL6467947 | 0.85 | RIPK2 (0.53) | KDRRETKIF5BKCNH2CCDC6 | |
| SCHEMBL6461293 | 0.84 | SRC (0.54) | KDRRETKIF5BKCNH2CCDC6 | |
| Carbamic Acid SCHEMBL7852916 | 0.84 | SRC (0.60) | KDRRETKIF5BKCNH2CCDC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713474-B2 | SERINE-THREONINE AND TYROSINE KINASE INHIBITORS | ABBOTT GMBH & CO. KG (DE) | 2004-03-30 | — | — | US | disclosed |