Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 1.00 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.81 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.81 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | GMNN | O75496 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | THPO | P40225 | 1/20 | 0.63 |
| ▸ | MTOR | P42345 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | CETP | P11597 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | UBE2N | P61088 | 1/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5272976 | 1.00 | SPHK1 (1.00) | SPHK1TRPV1TRPA1CYP2D6TP53 | |
| Xetoaminol C SCHEMBL3190206 | 1.00 | SPHK1 (1.00) | SPHK1TRPV1TRPA1CYP2D6TP53 | |
| SCHEMBL5268617 | 1.00 | SPHK1 (1.00) | SPHK1TRPV1TRPA1CYP2D6TP53 | |
| SCHEMBL5276312 | 1.00 | SPHK1 (1.00) | SPHK1TRPV1TRPA1CYP2D6TP53 | |
| SCHEMBL5275118 | 1.00 | SPHK1 (1.00) | SPHK1TRPV1TRPA1CYP2D6TP53 | |
| SCHEMBL6865653 | 1.00 | SPHK1 (1.00) | SPHK1TRPV1TRPA1CYP2D6TP53 | |
| SCHEMBL6863016 | 1.00 | SPHK1 (1.00) | SPHK1TRPV1TRPA1CYP2D6TP53 | |
| SCHEMBL5654343 | 1.00 | SPHK1 (1.00) | SPHK1TRPV1TRPA1CYP2D6TP53 | |
| SCHEMBL5268271 | 1.00 | SPHK1 (1.00) | SPHK1TRPV1TRPA1CYP2D6TP53 | |
| Xetoaminol C SCHEMBL5271731 | 1.00 | SPHK1 (1.00) | SPHK1TRPV1TRPA1CYP2D6TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800661-B1 | Spisulosine compounds | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2004-10-05 | — | — | US | claimed |
| WO-2017077550-A1 | A METAL FREE PROCESS FOR THE PREPARATION OF ALPHA-SUBSTITUTED CARBONYL COMPOUNDS FROM ALKENES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-05-11 | — | — | WO | disclosed |