SCHEMBL6865862

SCHEMBL6865862

CCCCCCCCCCCCOc1ccc(-c2nc(-c3ccc(C)cc3C)nc(-c3ccc(C)cc3C)n2)c(O)c1.CCCCCCCCOc1ccc(-c2nc(-c3ccc(C)cc3)nc(-c3ccc(C)cc3)n2)c(O)c1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 4/20 0.45
NR5A1 Q13285 1/20 0.44
ACACB O00763 1/20 0.43
ACACA Q13085 1/20 0.43
PLK1 P53350 2/20 0.41
RARB P10826 3/20 0.41
NPC1 O15118 2/20 0.41
ALDH1A1 P00352 2/20 0.41
RAB9A P51151 2/20 0.41
KDM4E B2RXH2 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ALDH2 P05091 1/20 0.41
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CNR2 P34972 2/20 0.39
LTA4H P09960 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7698045 0.98 ACACB (0.46) PTPN11NR5A1ACACBACACAPLK1
SCHEMBL14998002 0.94 PTPN11 (0.47) PTPN11NR5A1PLK1RARBNPC1
SCHEMBL4413556 0.94 PTPN11 (0.49) PTPN11NR5A1PLK1RARBNPC1
SCHEMBL22216823 0.94 NR5A1 (0.49) PTPN11NR5A1PLK1NPC1ALDH1A1
SCHEMBL78927 0.94 NR5A1 (0.49) PTPN11NR5A1PLK1NPC1ALDH1A1
SCHEMBL6029292 0.94 NR5A1 (0.49) PTPN11NR5A1PLK1NPC1ALDH1A1
SCHEMBL45412 0.94 NR5A1 (0.49) PTPN11NR5A1PLK1NPC1ALDH1A1
SCHEMBL3893045 0.94 NR5A1 (0.49) PTPN11NR5A1PLK1NPC1ALDH1A1
SCHEMBL39014 0.94 PTPN11 (0.49) PTPN11NR5A1PLK1RARBNPC1
SCHEMBL3675957 0.94 PTPN11 (0.49) PTPN11NR5A1PLK1RARBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6806304-B2 OXIDATION RESISTANCE; DISCOLORATION INHIBITION CYTEC TECHNOLOGY CORP. 2004-10-19 US disclosed
EP-0601978-B1 Process for the preparation of 2,2,6,6-tetramethyl-4-piperidyloxy-1,3,5-triazines with two or more triazine rings CIBA GEIGY AG (CH) 1997-05-02 EP disclosed
US-5500024-A DISCOLORATION INHIBITION; INTRAOCULAR AND CONTACT LENSES; BONDED TO POLYMER CIBA-GEIGY CORPORATION (US) 1996-03-19 US disclosed
US-5399692-A Ultraviolet absorbing benzophenone sulfonic acid derivatives CIBA-GEIGY CORPORATION (US) 1995-03-21 US disclosed
US-5298033-A An absorber bonded to lens formed of hydroxyethyl methacrylate CIBA-GEIGY CORPORATION (US) 1994-03-29 US disclosed