Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 9/20 | 1.00 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.83 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.81 |
| ▸ | CA1 | P00915 | 2/20 | 0.76 |
| ▸ | CA2 | P00918 | 2/20 | 0.76 |
| ▸ | CA9 | Q16790 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 4/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.75 |
| ▸ | ESR1 | P03372 | 5/20 | 0.73 |
| ▸ | PGR | P06401 | 2/20 | 0.73 |
| ▸ | AR | P10275 | 2/20 | 0.73 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.73 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.73 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.73 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.73 |
| ▸ | ATM | Q13315 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| E2Mate SCHEMBL19272474 | 1.00 | STS (1.00) | STSABCC1ABCC4KDM4ECA1 | |
| E2Mate SCHEMBL628174 | 1.00 | STS (1.00) | STSABCC1ABCC4KDM4ECA1 | |
| E2Mate SCHEMBL5165269 | 1.00 | STS (1.00) | STSABCC1ABCC4KDM4ECA1 | |
| E2Mate SCHEMBL5980613 | 1.00 | STS (1.00) | STSABCC1ABCC4KDM4ECA1 | |
| E2Mate SCHEMBL29924099 | 1.00 | STS (1.00) | STSABCC1ABCC4KDM4ECA1 | |
| E2Mate SCHEMBL5151234 | 1.00 | STS (1.00) | STSABCC1ABCC4KDM4ECA1 | |
| E2Mate SCHEMBL10070158 | 1.00 | STS (1.00) | STSABCC1ABCC4KDM4ECA1 | |
| Emate SCHEMBL7164522 | 0.93 | STS (0.86) | STSABCC1ABCC4KDM4ECA1 | |
| E2Mate SCHEMBL15940838 | 0.91 | STS (0.83) | STSABCC1ABCC4KDM4ECA1 | |
| SCHEMBL232796 | 0.91 | ABCC4 (1.00) | STSABCC1ABCC4KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775155-B1 | ESTRA-1,3,5(10)-TRIENE DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING AG (DE) | 2004-05-06 | — | — | EP | claimed |
| US-6080735-A | SUITABLE FOR HORMONAL CONTRACEPTION AND CLIMACTERIC HORMONE REPLACEMENT THERAPY (HRT) AS WELL AS FOR TREATMENT OF GYNECOLOGICAL AND ANDROLOGICAL DISEASES | JENAPHARM GMBH & CO. KG (DE) | 2000-06-27 | — | — | US | claimed |
| EP-0775155-B1 | ESTRA-1,3,5(10)-TRIENE DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING AG (DE) | 2004-05-06 | — | — | EP | disclosed |
| US-6080735-A | SUITABLE FOR HORMONAL CONTRACEPTION AND CLIMACTERIC HORMONE REPLACEMENT THERAPY (HRT) AS WELL AS FOR TREATMENT OF GYNECOLOGICAL AND ANDROLOGICAL DISEASES | JENAPHARM GMBH & CO. KG (DE) | 2000-06-27 | — | — | US | disclosed |