Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.66 |
| ▸ | F7 | P08709 | 19/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 12/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 12/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 12/20 | 0.49 |
| ▸ | F2 | P00734 | 10/20 | 0.49 |
| ▸ | F3 | P13726 | 9/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7146759 | 1.00 | F10 (0.66) | F10F7PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL6866479 | 0.99 | F10 (0.65) | F10F7PRSS1PRSS2PRSS3 | |
| SCHEMBL7153306 | 0.91 | F10 (0.68) | F10F7PRSS1PRSS2PRSS3 | |
| SCHEMBL6871860 | 0.91 | F10 (0.68) | F10F7PRSS1PRSS2PRSS3 | |
| SCHEMBL6873575 | 0.91 | F10 (0.72) | F10F7PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL6871858 | 0.91 | F10 (0.67) | F10F7PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL6873566 | 0.91 | F10 (0.71) | F10F7PRSS1PRSS2PRSS3 | |
| SCHEMBL7151136 | 0.90 | F10 (0.74) | F10F7PRSS1PRSS2PRSS3 | |
| SCHEMBL6874427 | 0.90 | F10 (0.74) | F10F7PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL6874421 | 0.89 | F10 (0.73) | F10F7PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474391-A1 | WATER SOLUBLE PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003066588-A1 | WATER SOLUBLE PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-08-14 | — | — | WO | disclosed |