Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 8/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1599003 | 0.91 | HCRTR1 (0.44) | HCRTR1HCRTR2 | |
| SCHEMBL1597174 | 0.79 | CSNK1D (0.35) | HCRTR1 | |
| SCHEMBL6885164 | 0.78 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL6885170 | 0.78 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL1597966 | 0.78 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL1597669 | 0.78 | HCRTR1 (0.55) | HCRTR1HCRTR2 | |
| SCHEMBL1598185 | 0.76 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL1598899 | 0.76 | HCRTR1 (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL6866828 | 0.75 | HCRTR1 (0.52) | HCRTR1HCRTR2 | |
| SCHEMBL1597429 | 0.73 | HCRTR1 (0.38) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385845-A1 | N-AROYL CYCLIC AMINES | SMITHKLINE BEECHAM PLC (GB) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002090355-A1 | N-AROYL CYCLIC AMINES | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-11-14 | — | — | WO | disclosed |