Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 13/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 11/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | MELK | Q14680 | 1/20 | 0.35 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867205 | 1.00 | MCHR1 (0.43) | MCHR1MAPK14NPY5RKDM4ELMNA | |
| SCHEMBL6868737 | 0.90 | MCHR1 (0.44) | MCHR1NPY5RKDM4ELMNASMN1; SMN2 | |
| SCHEMBL6879941 | 0.89 | MCHR1 (0.43) | MCHR1NPY5RKDM4ELMNASMN1; SMN2 | |
| SCHEMBL6872629 | 0.85 | MCHR1 (0.47) | MCHR1NPY5RKDM4ELMNASMN1; SMN2 | |
| SCHEMBL6872636 | 0.85 | MCHR1 (0.47) | MCHR1NPY5RKDM4ELMNASMN1; SMN2 | |
| SCHEMBL6876704 | 0.84 | MCHR1 (0.43) | MCHR1NPY5RKDM4ELMNASMN1; SMN2 | |
| SCHEMBL6876711 | 0.84 | MCHR1 (0.43) | MCHR1NPY5RKDM4ELMNASMN1; SMN2 | |
| SCHEMBL6877861 | 0.83 | MCHR1 (0.43) | MCHR1NPY5RKDM4ELMNASMN1; SMN2 | |
| SCHEMBL27652826 | 0.82 | MCHR1 (0.43) | MCHR1MAPK14NPY5RKDM4ELMNA | |
| SCHEMBL27632549 | 0.81 | MCHR1 (0.44) | MCHR1NPY5RKDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |