Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.73 |
| ▸ | CASP2 | P42575 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.54 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15224160 | 0.92 | EPHX1 (0.63) | EPHX1CASP2EPHX2 | |
| SCHEMBL25225212 | 0.85 | EPHX1 (1.00) | EPHX1CASP2EPHX2 | |
| SCHEMBL25226893 | 0.85 | EPHX1 (1.00) | EPHX1CASP2EPHX2 | |
| SCHEMBL25271007 | 0.85 | EPHX1 (1.00) | EPHX1CASP2EPHX2 | |
| SCHEMBL25227881 | 0.85 | EPHX1 (1.00) | EPHX1CASP2EPHX2 | |
| SCHEMBL25277850 | 0.85 | EPHX1 (1.00) | EPHX1CASP2EPHX2 | |
| SCHEMBL25225195 | 0.85 | EPHX1 (1.00) | EPHX1CASP2EPHX2 | |
| SCHEMBL25270721 | 0.85 | EPHX1 (1.00) | EPHX1CASP2EPHX2 | |
| SCHEMBL25278283 | 0.85 | EPHX1 (1.00) | EPHX1CASP2EPHX2 | |
| SCHEMBL25228721 | 0.85 | EPHX1 (1.00) | EPHX1CASP2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452522-A2 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2004-09-01 | — | — | EP | disclosed |