⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975549 | 1.00 | — | — | |
| SCHEMBL1876074 | 1.00 | — | — | |
| SCHEMBL28329383 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL11209526 | 0.98 | — | — | |
| Ammonia Solution, Strong SCHEMBL28709595 | 0.98 | — | — | |
| SCHEMBL6100204 | 0.75 | — | — | |
| SCHEMBL11511608 | 0.75 | — | — | |
| SCHEMBL6672719 | 0.75 | — | — | |
| SCHEMBL308245 | 0.75 | — | — | |
| SCHEMBL14206111 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119876103-A | Nitrilase and application thereof in methionine synthesis | 万华化学集团股份有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-115851684-B | Nitrilase and application thereof in methionine synthesis | 万华化学集团股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| US-20240076267-A1 | Method for preparing 2-hydroxy-4-methylthiobutyronitrile or the selenium equivalent thereof, and applications | ADISSEO FRANCE S.A.S., (FR) | 2024-03-07 | — | — | US | claimed |
| US-11897836-B2 | Process for the preparation of methionine | EVONIK OPERATIONS GMBH (DE) | 2024-02-13 | — | — | US | claimed |
| CN-117247848-B | Bacterial strain for producing nitrilase, fermentation method and application | 鲁东大学 | 2024-01-30 | — | — | CN | claimed |
| CN-110088085-B | Method for producing methionine | 赢创运营有限公司 | 2024-01-19 | — | — | CN | claimed |
| EP-4301729-A1 | METHOD FOR PREPARING 2-HYDROXY-4-METHYLTHIOBUTYRONITRILE OR THE SELENIUM EQUIVALENT THEREOF, AND APPLICATIONS | Adisseo France S.A.S. (FR) | 2024-01-10 | — | — | EP | claimed |
| CN-117043139-A | Method for preparing 2-hydroxy-4-methylthiobutyronitrile or selenium equivalent thereof and application thereof | 安迪苏法国联合股份有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-116855481-A | Nitrilase mutant and application thereof in preparation of 2-amino-4-methylthiobutyric acid | 浙江工业大学 | 2023-10-10 | — | — | CN | claimed |
| CN-116283686-A | Combined preparation method of methionine or derivative thereof and tertiary butylamine compound | 山东新和成氨基酸有限公司 | 2023-06-23 | — | — | CN | claimed |
| US-6525036-B2 | Treating post-menopausal osteoporosis. | MERCK & CO., INC. | 2003-02-25 | — | — | US | claimed |
| US-6417395-B1 | Process for preparing methionine | AVENTIS ANIMAL NUTRITION S.A. (FR) | 2002-07-09 | — | — | US | claimed |
| US-20020052378-A1 | Novel compounds and compositions as protease inhibitors | Celera Corporation | 2002-05-02 | — | — | US | claimed |
| EP-1137784-A1 | METHOD FOR ISOLATING AND SELECTING GENES CODING FOR ENZYMES, AND SUITABLE CULTURE MEDIUM | AVENTIS ANIMAL NUTRITION S.A. (FR) | 2001-10-04 | — | — | EP | claimed |
| WO-2001010776-A1 | REDUCTIVE COMBUSTION OF AMMONIUM SALTS OF SULFURIC ACID | NOVUS INTERNATIONAL, INC. (US) | 2001-02-15 | — | — | WO | claimed |
| WO-2000036120-A1 | METHOD FOR ISOLATING AND SELECTING GENES CODING FOR ENZYMES, AND SUITABLE CULTURE MEDIUM | AVENTIS ANIMAL NUTRITION S.A. (FR) | 2000-06-22 | — | — | WO | claimed |
| US-4960932-A | HYDROLYSIS OF 4-METHYLMERCAPTO-2-AMINOBUTYRONITRILE AND 4-METHYLMERCAPTO-2-AMINOBUTYRAMIDE | A.E.C. (FR) | 1990-10-02 | — | — | US | claimed |
| EP-0228938-B1 | PROCESS FOR THE PREPARATION OF AN AQUEOUS SOLUTION OF AN ALKALINE METAL SALT OF METHIONINE | RHONE-POULENC NUTRITION ANIMALE (FR) | 1989-03-08 | — | — | EP | claimed |
| US-4095000-A | AMINO ACIDS AND DERIVATIVES, POLYHYDROXY COMPOUNDS, NUTRIENTS, HYDROLYSIS | Brenner, Max (CH) | 1978-06-13 | — | — | US | claimed |
| US-4064159-A | AMMONIATION OF CORRESPONDING ALPHA-HYDROXY DERIVATIVE | PRODUITS CHIMIQUES DU BEARN (FR) | 1977-12-20 | — | — | US | claimed |