Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 7/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 8/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MELK | Q14680 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6868236 | 1.00 | NPY5R (0.43) | NPY5RMCHR1POLBADRA2AACACB | |
| SCHEMBL6877053 | 0.95 | KDR (0.42) | NPY5RMCHR1POLBADRA2AACACB | |
| SCHEMBL6877062 | 0.95 | KDR (0.42) | NPY5RMCHR1POLBADRA2AACACB | |
| SCHEMBL6463959 | 0.94 | NPY5R (0.44) | NPY5RMCHR1POLBADRA2AACACB | |
| SCHEMBL6463955 | 0.94 | NPY5R (0.44) | NPY5RMCHR1POLBADRA2AACACB | |
| SCHEMBL6464772 | 0.93 | MCHR1 (0.41) | NPY5RMCHR1POLBADRA2AACACB | |
| SCHEMBL6459092 | 0.93 | MCHR1 (0.41) | NPY5RMCHR1POLBADRA2AACACB | |
| SCHEMBL6878437 | 0.91 | NPY5R (0.43) | NPY5RMCHR1POLBADRA2AACACB | |
| SCHEMBL6878430 | 0.91 | NPY5R (0.43) | NPY5RMCHR1POLBADRA2AACACB | |
| SCHEMBL6456892 | 0.91 | MEN1 (0.42) | NPY5RMCHR1POLBADRA2AACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |