Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.43 |
| ▸ | HRH1 | P35367 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6876406 | 0.91 | MAPT (0.49) | EPHX2NPC1ALDH1A1SMN1; SMN2MCHR1 | |
| SCHEMBL6876402 | 0.91 | MAPT (0.49) | EPHX2NPC1ALDH1A1SMN1; SMN2MCHR1 | |
| SCHEMBL6875563 | 0.91 | MEN1 (0.56) | EPHX2NPC1ALDH1A1SMN1; SMN2MCHR1 | |
| SCHEMBL6875557 | 0.91 | MEN1 (0.56) | EPHX2NPC1ALDH1A1SMN1; SMN2MCHR1 | |
| SCHEMBL6873414 | 0.91 | EPHX2 (0.43) | EPHX2NPC1ALDH1A1SMN1; SMN2MCHR1 | |
| SCHEMBL6873409 | 0.91 | EPHX2 (0.43) | EPHX2NPC1ALDH1A1SMN1; SMN2MCHR1 | |
| SCHEMBL6873819 | 0.91 | EPHX1 (0.53) | EPHX2NPC1ALDH1A1SMN1; SMN2MCHR1 | |
| SCHEMBL6873818 | 0.91 | EPHX1 (0.53) | EPHX2NPC1ALDH1A1SMN1; SMN2MCHR1 | |
| SCHEMBL6874878 | 0.90 | NPC1 (0.54) | EPHX2NPC1ALDH1A1SMN1; SMN2MCHR1 | |
| SCHEMBL6874872 | 0.90 | NPC1 (0.54) | EPHX2NPC1ALDH1A1SMN1; SMN2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |