Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 14/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.51 |
| ▸ | HTR2B | P41595 | 4/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.51 |
| ▸ | HRH1 | P35367 | 3/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.39 |
| ▸ | PHF13 | Q86YI8 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6458362 | 0.88 | MCHR1 (0.52) | MCHR1ADRA2AHTR2BADRA1AHRH1 | |
| SCHEMBL6458370 | 0.88 | MCHR1 (0.52) | MCHR1ADRA2AHTR2BADRA1AHRH1 | |
| SCHEMBL6464596 | 0.88 | MCHR1 (0.56) | MCHR1ADRA2AHTR2BADRA1AHRH1 | |
| SCHEMBL6464603 | 0.88 | MCHR1 (0.56) | MCHR1ADRA2AHTR2BADRA1AHRH1 | |
| SCHEMBL6875374 | 0.88 | MCHR1 (0.54) | MCHR1ADRA2AHTR2BADRA1AHRH1 | |
| SCHEMBL6875373 | 0.88 | MCHR1 (0.54) | MCHR1ADRA2AHTR2BADRA1AHRH1 | |
| SCHEMBL6875077 | 0.84 | MCHR1 (0.71) | MCHR1ADRA2AHTR2BADRA1AHRH1 | |
| SCHEMBL6877794 | 0.84 | MCHR1 (0.65) | MCHR1ADRA2AHTR2BADRA1AHRH1 | |
| SCHEMBL6875080 | 0.84 | MCHR1 (0.71) | MCHR1ADRA2AHTR2BADRA1AHRH1 | |
| SCHEMBL6877798 | 0.84 | MCHR1 (0.65) | MCHR1ADRA2AHTR2BADRA1AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |