Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | CASP2 | P42575 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4625755 | 1.00 | KMT2A (0.65) | KMT2AKDM4EMEN1MAPTPOLB | |
| Hydrochloric Acid SCHEMBL5408274 | 0.99 | KMT2A (0.64) | KMT2AKDM4EMEN1MAPTPOLB | |
| SCHEMBL4627215 | 0.86 | TRPV1 (0.52) | KMT2AKDM4EMEN1MAPTPOLB | |
| SCHEMBL4628336 | 0.85 | NPC1 (0.51) | KMT2AKDM4EMEN1MAPTPOLB | |
| Hydrochloric Acid SCHEMBL5403706 | 0.85 | TRPV1 (0.51) | KMT2AKDM4EMEN1MAPTPOLB | |
| SCHEMBL6968097 | 0.84 | KDM4E (0.60) | KMT2AKDM4EMEN1MAPTPOLB | |
| Iodide SCHEMBL5418758 | 0.84 | NPC1 (0.50) | KMT2AKDM4EMEN1MAPTPOLB | |
| Hydrochloric Acid SCHEMBL5400931 | 0.83 | MEN1 (0.46) | KMT2AKDM4EMEN1MAPTPOLB | |
| SCHEMBL6969347 | 0.82 | KDM4E (0.58) | KMT2AKDM4EMEN1MAPTPOLB | |
| SCHEMBL4625924 | 0.82 | MEN1 (0.60) | KMT2AKDM4EMEN1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6809090-B2 | NITROGEN MONOXIDE SYNTHASE AND/OR LIPIDIC PEROXIDATION INHIBITORS | IPSEN PHARMA S.A.S. (FR) | 2004-10-26 | — | — | US | disclosed |