Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869460 | 1.00 | DPP4 (0.53) | DPP4ALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL6852732 | 0.82 | DPP4 (0.57) | DPP4ALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL12266048 | 0.78 | SMN1; SMN2 (0.42) | ALDH1A1KDM4EGAAGLAMAPT | |
| SCHEMBL8571848 | 0.77 | DPP4 (0.59) | DPP4ALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL6847977 | 0.75 | PRF1 (0.41) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL6853766 | 0.75 | HDAC1 (0.40) | KDM4EGLAMAPTNPC1RAB9A | |
| SCHEMBL6853779 | 0.75 | HDAC1 (0.40) | KDM4EGLAMAPTNPC1RAB9A | |
| SCHEMBL6853774 | 0.75 | HDAC1 (0.40) | KDM4EGLAMAPTNPC1RAB9A | |
| SCHEMBL6847972 | 0.75 | PRF1 (0.41) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL6847980 | 0.75 | PRF1 (0.41) | ALDH1A1KDM4EHSD17B10MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825170-B2 | ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-30 | — | — | US | disclosed |