Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869176 | 0.93 | ADORA2A (0.73) | ADORA2A | |
| SCHEMBL6870109 | 0.91 | ADORA2A (0.72) | ADORA2A | |
| SCHEMBL6871719 | 0.91 | ADORA2A (0.66) | ADORA2A | |
| SCHEMBL6867665 | 0.91 | ADORA2A (0.62) | ADORA2A | |
| SCHEMBL6871932 | 0.90 | ADORA2A (0.65) | ADORA2A | |
| SCHEMBL6871527 | 0.89 | ADORA2A (0.61) | ADORA2A | |
| SCHEMBL6874228 | 0.89 | ADORA2A (0.58) | ADORA2A | |
| SCHEMBL6873805 | 0.88 | ADORA2A (0.62) | ADORA2A | |
| SCHEMBL6871542 | 0.88 | ADORA2A (0.66) | ADORA2A | |
| SCHEMBL6870179 | 0.86 | ADORA2A (0.57) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | claimed |