Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6871876 | 0.99 | ADORA2A (0.61) | ADORA2AITK | |
| SCHEMBL6869830 | 0.88 | ADORA2A (0.72) | ADORA2A | |
| SCHEMBL6871519 | 0.87 | ADORA2A (0.51) | ADORA2A | |
| SCHEMBL6870337 | 0.85 | ADORA2A (0.76) | ADORA2A | |
| SCHEMBL6863087 | 0.84 | ADORA2A (0.76) | ADORA2A | |
| SCHEMBL6863095 | 0.83 | ADORA2A (0.67) | ADORA2A | |
| SCHEMBL6872071 | 0.81 | ADORA2A (0.64) | ADORA2A | |
| SCHEMBL6869915 | 0.80 | ADORA2A (0.57) | ADORA2AITK | |
| SCHEMBL6871208 | 0.78 | F2 (0.39) | ADORA2AITK | |
| SCHEMBL6867483 | 0.77 | ADORA2A (0.79) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | claimed |
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |
| US-6506772-B1 | Pharmaceutically active salts thereof with activity as adenosine receptor ligands are disclosed. These compounds are the adenosine receptor. | HOFFMANN-LA ROCHE INC. | 2003-01-14 | — | — | US | disclosed |