Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 17/20 | 0.52 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.42 |
| ▸ | TACR3 | P29371 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869431 | 0.96 | TACR1 (0.52) | TACR1GPBAR1TACR3 | |
| SCHEMBL6871260 | 0.91 | TACR1 (0.51) | TACR1GPBAR1 | |
| SCHEMBL7039431 | 0.89 | TACR1 (0.41) | TACR1 | |
| SCHEMBL6016667 | 0.89 | TACR1 (0.49) | TACR1GPBAR1TACR3 | |
| SCHEMBL6870660 | 0.87 | TACR1 (0.52) | TACR1GPBAR1 | |
| SCHEMBL7039564 | 0.85 | TACR1 (0.41) | TACR1 | |
| SCHEMBL6871465 | 0.85 | TACR1 (0.49) | TACR1GPBAR1TACR3 | |
| SCHEMBL6871717 | 0.85 | TACR1 (0.46) | TACR1GPBAR1TACR3 | |
| SCHEMBL6873362 | 0.85 | TACR1 (0.51) | TACR1GPBAR1TACR3 | |
| SCHEMBL6868260 | 0.85 | GPBAR1 (0.42) | TACR1GPBAR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187814-B1 | 5-PHENYL-PYRIMIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2004-08-18 | — | — | EP | claimed |