Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6870390 | 0.95 | PARP1 (0.71) | PARP1PARP2 | |
| SCHEMBL6873579 | 0.89 | PARP1 (0.70) | PARP1PARP2 | |
| SCHEMBL6872357 | 0.88 | PARP1 (0.52) | PARP1PARP2 | |
| SCHEMBL6872852 | 0.85 | PARP1 (0.72) | PARP1PARP2 | |
| SCHEMBL5622259 | 0.85 | PARP1 (0.88) | PARP1PARP2 | |
| SCHEMBL6864320 | 0.84 | PARP1 (0.57) | PARP1PARP2 | |
| SCHEMBL6872932 | 0.82 | PARP1 (0.52) | PARP1 | |
| SCHEMBL6871606 | 0.82 | PARP1 (0.74) | PARP1PARP2 | |
| SCHEMBL6871591 | 0.82 | PARP1 (0.56) | PARP1PARP2 | |
| SCHEMBL6864930 | 0.82 | PARP1 (0.65) | PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133477-B1 | SUBSTITUTED BENZIMIDAZOLES AND THEIR USE AS PARP INHIBITORS | ABBOTT GMBH & CO KG (DE) | 2004-02-18 | — | — | EP | disclosed |