Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6871214 | 0.99 | ADORA2A (1.00) | ADORA2AADORA1 | |
| SCHEMBL6870560 | 0.90 | ADORA2A (0.84) | ADORA2A | |
| SCHEMBL6867809 | 0.88 | ADORA2A (1.00) | ADORA2A | |
| SCHEMBL6867660 | 0.88 | ADORA2A (1.00) | ADORA2A | |
| SCHEMBL6863638 | 0.88 | ADORA2A (1.00) | ADORA2A | |
| SCHEMBL6869305 | 0.88 | ADORA2A (0.79) | ADORA2A | |
| SCHEMBL6867961 | 0.87 | ADORA2A (1.00) | ADORA2A | |
| SCHEMBL6873003 | 0.87 | ADORA2A (0.78) | ADORA2A | |
| SCHEMBL6870333 | 0.85 | ADORA2A (0.75) | ADORA2A | |
| SCHEMBL6873028 | 0.84 | ADORA2A (0.73) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |
| US-6506772-B1 | Pharmaceutically active salts thereof with activity as adenosine receptor ligands are disclosed. These compounds are the adenosine receptor. | HOFFMANN-LA ROCHE INC. | 2003-01-14 | — | — | US | disclosed |