Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 10/20 | 0.44 |
| ▸ | HMGCR | P04035 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PDE6D | O43924 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10129494 | 0.88 | GCGR (0.46) | GCGRHMGCRALDH1A1CYP3A4PDE6D | |
| SCHEMBL13637067 | 0.86 | KDM5B (0.40) | GCGRHMGCRALDH1A1CYP3A4PDE6D | |
| SCHEMBL14045937 | 0.83 | GCGR (0.54) | GCGRHMGCRALDH1A1CYP3A4PDE6D | |
| SCHEMBL14315362 | 0.82 | ADORA1 (0.44) | HMGCRALDH1A1CYP3A4PDE6DNR1I2 | |
| SCHEMBL12617063 | 0.81 | HMGCR (0.46) | GCGRHMGCRALDH1A1CYP3A4PDE6D | |
| SCHEMBL13010709 | 0.81 | GCGR (0.43) | GCGRHMGCRALDH1A1CYP3A4PDE6D | |
| SCHEMBL431291 | 0.81 | HMGCR (0.55) | GCGRHMGCRALDH1A1CYP3A4PDE6D | |
| SCHEMBL12288575 | 0.80 | GCGR (0.40) | GCGRHMGCRALDH1A1CYP3A4PDE6D | |
| SCHEMBL15024879 | 0.79 | GCGR (0.41) | GCGRHMGCRALDH1A1CYP3A4PDE6D | |
| SCHEMBL7913752 | 0.79 | HMGCR (0.46) | GCGRHMGCRALDH1A1CYP3A4PDE6D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011083495-A2 | PROCESS FOR THE PREPARATION OF DIHYDROXY PROTECTED DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | MSN LABORATORIES LIMITED (IN) | 2011-07-14 | — | — | WO | disclosed |
| US-20090275752-A1 | Novel Process for Statins and its Pharmaceutically Acceptable Salts Thereof | MSN LABORATORIES LIMITED (IN) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275752-A1 | Novel Process for Statins and its Pharmaceutically Acceptable Salts Thereof | HMGCR, NPC1L1, PCSK9 | GCGR 1528/4885HMGCR 1/4885ALDH1A1 1466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.