Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 5/20 | 0.46 |
| ▸ | F12 | P00748 | 3/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6870680 | 0.90 | ADORA2A (0.60) | ADORA2AKMT2AF2F12ALDH1A1 | |
| SCHEMBL6870369 | 0.89 | ADORA2A (0.61) | ADORA2AF2F12 | |
| SCHEMBL6868951 | 0.88 | ADORA2A (0.56) | ADORA2AF2F12F10KLKB1 | |
| SCHEMBL6863726 | 0.88 | ADORA2A (0.56) | ADORA2AF2F12ALDH1A1F10 | |
| SCHEMBL6870552 | 0.87 | ADORA2A (0.57) | ADORA2AF2F12 | |
| SCHEMBL6871898 | 0.87 | ADORA2A (0.62) | ADORA2AMEN1KMT2AF2F12 | |
| SCHEMBL6872164 | 0.86 | ADORA2A (0.59) | ADORA2AMEN1KMT2AAPOBEC3AALDH1A1 | |
| SCHEMBL6863344 | 0.86 | ADORA2A (0.63) | ADORA2AF2F12 | |
| SCHEMBL6872326 | 0.85 | ADORA2A (0.57) | ADORA2AF2F12 | |
| SCHEMBL6873020 | 0.85 | ADORA2A (0.53) | ADORA2AF2F12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |