Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 9/20 | 0.50 |
| ▸ | FNTA | P49354 | 8/20 | 0.49 |
| ▸ | FNTB | P49356 | 8/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6868055 | 0.84 | FNTA (0.63) | CYP19A1FNTAFNTBCYP1A2CYP3A4 | |
| SCHEMBL6870980 | 0.81 | FNTA (0.60) | CYP19A1FNTAFNTBCYP1A2CYP3A4 | |
| SCHEMBL5164053 | 0.78 | FNTA (0.46) | CYP19A1FNTAFNTBCYP1A2CYP3A4 | |
| SCHEMBL6867606 | 0.76 | FNTA (0.67) | CYP19A1FNTAFNTBCYP1A2CYP3A4 | |
| SCHEMBL4144550 | 0.75 | FNTA (0.51) | CYP19A1FNTAFNTBCYP1A2CYP3A4 | |
| SCHEMBL7210122 | 0.74 | FNTA (0.54) | CYP19A1FNTAFNTBCYP1A2CYP3A4 | |
| SCHEMBL6169572 | 0.74 | FNTA (0.53) | CYP19A1FNTAFNTB | |
| SCHEMBL4156125 | 0.74 | FNTA (0.85) | CYP19A1FNTAFNTBCYP1A2CYP3A4 | |
| SCHEMBL3521134 | 0.74 | FNTA (0.56) | CYP19A1FNTAFNTBCYP1A2CYP3A4 | |
| SCHEMBL6871485 | 0.73 | FNTA (0.51) | FNTAFNTBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1106610-B1 | Farnesyl transferase inhibiting 2-quinolone derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2004-06-16 | — | — | EP | claimed |
| EP-1019395-B1 | FARNESYL TRANSFERASE INHIBITING 2-QUINOLONE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2002-01-30 | — | — | EP | claimed |