Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CTSA | P10619 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688245 | 0.91 | PTGER3 (0.46) | PTGER3MAPTCTSAALDH1A1 | |
| SCHEMBL688258 | 0.87 | PTGER3 (0.45) | PTGER3MAPTCTSAALDH1A1 | |
| SCHEMBL687904 | 0.86 | PTGER3 (0.47) | PTGER3MAPTCTSAALDH1A1SMN1; SMN2 | |
| SCHEMBL688137 | 0.86 | KDM4E (0.42) | PTGER3CTSAALDH1A1KDM4EMAPK1 | |
| SCHEMBL687909 | 0.85 | SMN1; SMN2 (0.49) | PTGER3MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL687114 | 0.85 | PTGER3 (0.45) | PTGER3MAPTCTSAALDH1A1SMN1; SMN2 | |
| SCHEMBL687333 | 0.85 | PTGER3 (0.47) | PTGER3MAPTCTSAALDH1A1KDM4E | |
| SCHEMBL688289 | 0.85 | PTGER3 (0.47) | PTGER3MAPTALDH1A1KDM4EMAPK1 | |
| SCHEMBL687711 | 0.84 | PTGER3 (0.45) | PTGER3MAPTCTSAALDH1A1SMN1; SMN2 | |
| SCHEMBL687524 | 0.84 | PTGER3 (0.45) | PTGER3MAPTCTSAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |