Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19111926 | 0.83 | NOTUM (0.63) | NOTUMNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL4865565 | 0.77 | NOTUM (1.00) | NOTUMNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL14122701 | 0.77 | NOTUM (0.63) | NOTUMNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL10130649 | 0.76 | NOTUM (0.62) | NOTUMNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8433805 | 0.76 | NOTUM (0.57) | NOTUMNPC1RAB9ASMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL8437873 | 0.75 | NOTUM (0.56) | NOTUMNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9005927 | 0.74 | NOTUM (0.74) | NOTUMNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL7585415 | 0.73 | NPC1 (0.79) | NOTUMNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6206857 | 0.72 | NOTUM (0.60) | NOTUMNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL21776935 | 0.72 | NOTUM (0.70) | NOTUMNPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2470514-B1 | PSEUDO-DIPEPTIDES AS MMP INHIBITORS | COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-07-12 | — | — | EP | disclosed |
| WO-2011023864-A1 | PSEUDODIPEPTIDES AS MMP INHIBITORS | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2011-03-03 | — | — | WO | disclosed |