Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL30618014 | 0.96 | CA1 (0.50) | — | |
| Acetamidine SCHEMBL10602854 | 0.84 | — | — | |
| Nitrous Acid SCHEMBL687168 | 0.81 | — | — | |
| Pimagedine SCHEMBL686876 | 0.78 | — | — | |
| Urea SCHEMBL8835038 | 0.76 | — | — | |
| Guanidine SCHEMBL27640020 | 0.75 | — | — | |
| Nitrous Acid SCHEMBL28486015 | 0.75 | — | — | |
| Nitrous Acid SCHEMBL28400090 | 0.75 | — | — | |
| Nitrous Acid SCHEMBL2213450 | 0.75 | — | — | |
| Nitrous Acid SCHEMBL2381719 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286881-A1 | PYROTECHNIC COMPOSITIONS AND METHODS OF MAKING THE SAME | AUTOLIV ASP, INC. (US) | 2023-09-14 | — | — | US | claimed |
| CN-116731896-A | Bacillus coagulans capable of degrading ethanol and application thereof | 南京财经大学 | 2023-09-12 | — | — | CN | claimed |
| CN-111183534-A | Flame retardant separator for secondary battery | 株式会社LG化学 | 2020-05-19 | — | — | CN | claimed |
| CN-104974727-B | Inhibit the medicament of alienation metabolism sulfate reducing bacteria and its prepares and methods for using them | 天津亿利科能源科技发展股份有限公司 | 2018-08-24 | — | — | CN | claimed |
| CN-104974727-A | Medicament for inhibiting dissimilatory metabolic sulfate reducing bacteria and preparation and application methods thereof | E TECH ENERGY TECHNOLOGY DEV CORP | 2015-10-14 | — | — | CN | claimed |
| EP-2862217-A1 | ELECTROCHEMICAL CELLS COMPRISING ELECTROLYTE ADDITIVES AND IONOMER ARTICLES, !AND METHODS FOR MAKING AND USING THE SAME | E. I. Du Pont de Nemours and Company (US) | 2015-04-22 | — | — | EP | claimed |
| CN-104541388-A | Electrochemical cells comprising electrolyte additives, and methods for making and using the same | DU PONT | 2015-04-22 | — | — | CN | claimed |
| WO-2013191790-A1 | ELECTROCHEMICAL CELLS COMPRISING ELECTROLYTE ADDITIVES AND IONOMER ARTICLES, |AND METHODS FOR MAKING AND USING THE SAME | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-12-27 | — | — | WO | claimed |
| US-8212056-B2 | Ligands for transition-metals and methods of use | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2012-07-03 | — | — | US | claimed |
| CN-102153997-A | Hydrogen sulfide treating agent for oil fields and method for treating hydrogen sulfide | TECH OILFIELD TECHNOLOGY DEV CO LTD E | 2011-08-17 | — | — | CN | claimed |
| US-20090326243-A1 | Ligands for transition-metals and methods of use | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2009-12-31 | — | — | US | claimed |
| US-20260072348-A1 | PHOTOCURING AGENTS | MERCK PATENT GMBH (DE) | 2026-03-12 | — | — | US | disclosed |
| US-12485169-B2 | Compounds | Grey Wolf Therapeutics Limited (GB) | 2025-12-02 | — | — | US | disclosed |
| CN-120025279-A | Compounds capable of modulating endoplasmic reticulum aminopeptidase 1 | 格雷沃尔夫治疗有限公司 | 2025-05-23 | — | — | CN | disclosed |
| CN-119265090-B | Emthoxymanella welti condensation for high-efficiency metabolism of ethanol and application thereof | 北京和益源生物技术有限公司 | 2025-04-22 | — | — | CN | disclosed |
| US-4535095-A | BLENDING A CURABLE MIXTURE | ETHYL CORPORATION (US) | 1985-08-13 | — | — | US | disclosed |
| WO-1985000670-A1 | THERMAL DEVELOPMENT OF PHOTOSENSITIVE MATERIALS EMPLOYING MICROENCAPSULATED RADIATION SENSITIVE COMPOSITIONS | THE MEAD CORPORATION (US) | 1985-02-14 | — | — | WO | disclosed |
| EP-0107064-A1 | Process for making low density chlorinated polyvinyl chloride foam | The B.F. GOODRICH Company (US) | 1984-05-02 | — | — | EP | disclosed |
| US-4413065-A | BLOWING AGENT; ALKALI METAL BOROHYDRIDE; HYDRATED SALT OR ORGANIC ACID | THE B. F. GOODRICH COMPANY (US) | 1983-11-01 | — | — | US | disclosed |
| US-4383048-A | Process for making low density chlorinated polyvinyl chloride foam | THE B. F. GOODRICH COMPANY (US) | 1983-05-10 | — | — | US | disclosed |