Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6873189 | 1.00 | TACR1 (0.85) | TACR1 | |
| SCHEMBL6098937 | 0.93 | TACR1 (0.85) | TACR1 | |
| SCHEMBL6098939 | 0.93 | TACR1 (0.85) | TACR1 | |
| SCHEMBL6100524 | 0.92 | TACR1 (1.00) | TACR1 | |
| SCHEMBL6100519 | 0.92 | TACR1 (1.00) | TACR1 | |
| SCHEMBL6100460 | 0.89 | TACR1 (0.85) | TACR1 | |
| SCHEMBL6100465 | 0.89 | TACR1 (0.85) | TACR1 | |
| SCHEMBL6099617 | 0.88 | TACR1 (0.92) | TACR1 | |
| SCHEMBL6099620 | 0.88 | TACR1 (0.92) | TACR1 | |
| SCHEMBL6098400 | 0.85 | TACR1 (0.87) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406894-B1 | PIPERAZINE OXIME DERIVATIVES HAVING NK-1 RECEPTOR ANTAGONISTIC ACTIVITY | SOLVAY PHARM BV (NL) | 2004-12-22 | — | — | EP | disclosed |
| EP-1406894-A1 | PIPERAZINE OXIME DERIVATIVES HAVING NK-1 RECEPTOR ANTAGONISTIC ACTIVITY | Solvay Pharmaceuticals B.V. (NL) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003006459-A1 | PIPERAZINE OXIME DERIVATIVES HAVING NK-1 RECEPTOR ANTAGONISTIC ACTIVITY | SOLVAY PHARMACEUTICALS B.V. (NL) | 2003-01-23 | — | — | WO | disclosed |