Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 19/20 | 0.81 |
| ▸ | ADRA2A | P08913 | 10/20 | 0.73 |
| ▸ | HTR2B | P41595 | 7/20 | 0.73 |
| ▸ | HRH1 | P35367 | 6/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.73 |
| ▸ | HTR1A | P08908 | 2/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6873290 | 1.00 | MCHR1 (0.81) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6874697 | 0.93 | MCHR1 (0.81) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6874703 | 0.93 | MCHR1 (0.81) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6463334 | 0.90 | MCHR1 (1.00) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6463341 | 0.90 | MCHR1 (1.00) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6463145 | 0.90 | MCHR1 (0.89) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6463138 | 0.90 | MCHR1 (0.89) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6461753 | 0.89 | MCHR1 (0.82) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6878277 | 0.89 | MCHR1 (0.64) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6878274 | 0.89 | MCHR1 (0.64) | MCHR1ADRA2AHTR2BHRH1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |