Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.58 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | ALPL | P05186 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ALPG | P10696 | 1/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | GALK1 | P51570 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.54 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.54 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3046506 | 1.00 | SLC6A2 (0.58) | SLC6A2SYNJ2KDM4EABL1ALPL | |
| SCHEMBL6859149 | 1.00 | SLC6A2 (0.58) | SLC6A2SYNJ2KDM4EABL1ALPL | |
| SCHEMBL4318187 | 1.00 | SLC6A2 (0.58) | SLC6A2SYNJ2KDM4EABL1ALPL | |
| SCHEMBL3046511 | 1.00 | SLC6A2 (0.58) | SLC6A2SYNJ2KDM4EABL1ALPL | |
| SCHEMBL8727122 | 1.00 | SLC6A2 (0.58) | SLC6A2SYNJ2KDM4EABL1ALPL | |
| SCHEMBL6367492 | 1.00 | SLC6A2 (0.58) | SLC6A2SYNJ2KDM4EABL1ALPL | |
| SCHEMBL5032458 | 1.00 | SLC6A2 (0.58) | SLC6A2SYNJ2KDM4EABL1ALPL | |
| SCHEMBL5032455 | 1.00 | SLC6A2 (0.58) | SLC6A2SYNJ2KDM4EABL1ALPL | |
| SCHEMBL7143078 | 1.00 | SLC6A2 (0.58) | SLC6A2SYNJ2KDM4EABL1ALPL | |
| SCHEMBL6865171 | 1.00 | SLC6A2 (0.58) | SLC6A2SYNJ2KDM4EABL1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832091-B1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA SICOR INC (US) | 2004-01-14 | — | — | EP | disclosed |
| EP-0832091-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA, INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040705-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA SICOR (US) | 1996-12-19 | — | — | WO | disclosed |