Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 18/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687261 | 0.93 | PTGER3 (0.62) | PTGER3CYP1A2KDM4EALDH1A1MAPK1 | |
| SCHEMBL688027 | 0.91 | PTGER3 (0.67) | PTGER3CYP1A2KDM4EALDH1A1MAPK1 | |
| SCHEMBL688122 | 0.91 | PTGER3 (0.67) | PTGER3CYP1A2KDM4EALDH1A1MAPK1 | |
| SCHEMBL687891 | 0.90 | PTGER3 (0.69) | PTGER3CYP1A2KDM4EALDH1A1MAPK1 | |
| SCHEMBL688360 | 0.90 | PTGER3 (0.62) | PTGER3CYP1A2KDM4EALDH1A1MAPK1 | |
| SCHEMBL687785 | 0.88 | PTGER3 (0.61) | PTGER3CYP1A2KDM4EALDH1A1MAPK1 | |
| SCHEMBL688031 | 0.88 | PTGER3 (0.60) | PTGER3CYP1A2KDM4EALDH1A1MAPK1 | |
| SCHEMBL686675 | 0.86 | PTGER3 (0.64) | PTGER3CYP1A2KDM4EALDH1A1MAPK1 | |
| SCHEMBL687732 | 0.86 | PTGER3 (0.49) | PTGER3CYP1A2KDM4EALDH1A1MAPK1 | |
| SCHEMBL687721 | 0.86 | PTGER3 (0.62) | PTGER3CYP1A2KDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1176956-B1 | CARBOXYLIC ACID DERIVATIVES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | ENCYSIVE PHARMACEUTICALS INC (US) | 2008-01-09 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |