Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 20/20 | 0.80 |
| ▸ | ADRA2A | P08913 | 12/20 | 0.80 |
| ▸ | HTR2B | P41595 | 9/20 | 0.80 |
| ▸ | HRH1 | P35367 | 8/20 | 0.80 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.74 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6874268 | 1.00 | MCHR1 (0.80) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6457538 | 0.94 | MCHR1 (0.80) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6457554 | 0.94 | MCHR1 (0.80) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| Hydrochloric Acid SCHEMBL6461443 | 0.93 | MCHR1 (0.78) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| Hydrochloric Acid SCHEMBL6461451 | 0.93 | MCHR1 (0.78) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6462200 | 0.91 | MCHR1 (0.84) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6462205 | 0.91 | MCHR1 (0.84) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| Hydrochloric Acid SCHEMBL6466371 | 0.91 | MCHR1 (0.82) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| Hydrochloric Acid SCHEMBL6459832 | 0.91 | MCHR1 (0.74) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| Hydrochloric Acid SCHEMBL6463368 | 0.91 | MCHR1 (0.82) | MCHR1ADRA2AHTR2BHRH1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |