Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.66 |
| ▸ | F7 | P08709 | 19/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 12/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 12/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 12/20 | 0.55 |
| ▸ | F3 | P13726 | 8/20 | 0.55 |
| ▸ | F2 | P00734 | 11/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL6875565 | 0.92 | F10 (0.57) | F10F7PRSS1PRSS2PRSS3 | |
| SCHEMBL6866388 | 0.92 | F10 (0.62) | F10F7PRSS1PRSS2PRSS3 | |
| SCHEMBL6866593 | 0.89 | F10 (0.81) | F10F7PRSS1PRSS2PRSS3 | |
| SCHEMBL6874456 | 0.88 | F10 (0.67) | F10F7PRSS1PRSS2PRSS3 | |
| SCHEMBL6872459 | 0.86 | F10 (0.65) | F10F7PRSS1PRSS2PRSS3 | |
| SCHEMBL6873215 | 0.85 | F10 (0.54) | F10F7PRSS1PRSS2PRSS3 | |
| SCHEMBL7143434 | 0.84 | F10 (0.73) | F10F7PRSS1PRSS2PRSS3 | |
| SCHEMBL7147264 | 0.84 | F10 (0.73) | F10F7PRSS1PRSS2PRSS3 | |
| SCHEMBL5882814 | 0.84 | F10 (0.73) | F10F7PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL6873211 | 0.84 | F10 (0.53) | F10F7PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474391-A1 | WATER SOLUBLE PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003066588-A1 | WATER SOLUBLE PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-08-14 | — | — | WO | disclosed |