Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | ACACB | O00763 | 13/20 | 0.44 |
| ▸ | ACACA | Q13085 | 12/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875316 | 1.00 | MCHR1 (0.48) | MCHR1NPY5RADRA2AACACBACACA | |
| SCHEMBL6878858 | 0.89 | MCHR1 (0.51) | MCHR1NPY5RADRA2AACACBACACA | |
| SCHEMBL6878852 | 0.89 | MCHR1 (0.51) | MCHR1NPY5RADRA2AACACBACACA | |
| SCHEMBL6876486 | 0.88 | MCHR1 (0.46) | MCHR1NPY5RADRA2AACACBACACA | |
| SCHEMBL6876478 | 0.88 | MCHR1 (0.46) | MCHR1NPY5RADRA2AACACBACACA | |
| SCHEMBL6876100 | 0.87 | NPY5R (0.47) | MCHR1NPY5RADRA2AACACBACACA | |
| SCHEMBL6868954 | 0.87 | MCHR1 (0.48) | MCHR1NPY5RADRA2AACACBACACA | |
| SCHEMBL6873100 | 0.87 | ACACB (0.47) | MCHR1NPY5RADRA2AACACBACACA | |
| SCHEMBL6873098 | 0.87 | ACACB (0.47) | MCHR1NPY5RADRA2AACACBACACA | |
| SCHEMBL6875795 | 0.87 | MCHR1 (0.46) | MCHR1NPY5RADRA2AACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |