Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 12/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 8/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875424 | 1.00 | MCHR1 (0.42) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6879274 | 0.90 | MCHR1 (0.42) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6879265 | 0.90 | MCHR1 (0.42) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6867920 | 0.89 | ACP1 (0.44) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6867914 | 0.89 | ACP1 (0.44) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6874786 | 0.88 | MCHR1 (0.49) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6874781 | 0.88 | MCHR1 (0.49) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6867311 | 0.86 | KDM4E (0.43) | MCHR1ADRA2ANPY5RKDM4ELMNA | |
| SCHEMBL6867313 | 0.86 | KDM4E (0.43) | MCHR1ADRA2ANPY5RKDM4ELMNA | |
| SCHEMBL4193669 | 0.86 | MCHR1 (0.57) | MCHR1ADRA2ANPY5RADRA1AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |