Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.57 |
| ▸ | F7 | P08709 | 19/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 11/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 11/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 11/20 | 0.48 |
| ▸ | F3 | P13726 | 4/20 | 0.48 |
| ▸ | F2 | P00734 | 11/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6873058 | 0.93 | F10 (0.66) | F10F7PRSS1PRSS2PRSS3 | |
| SCHEMBL7148989 | 0.87 | F10 (0.60) | F10F7PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7148983 | 0.86 | F10 (0.60) | F10F7PRSS1PRSS2PRSS3 | |
| SCHEMBL7145478 | 0.86 | F10 (0.62) | F10F7PRSS1PRSS2PRSS3 | |
| SCHEMBL7151893 | 0.86 | F10 (0.57) | F10F7PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7148944 | 0.85 | F10 (0.61) | F10F7PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL6876133 | 0.85 | F10 (0.56) | F10F7PRSS1PRSS2PRSS3 | |
| SCHEMBL7150858 | 0.81 | F10 (0.69) | F10F7PRSS1PRSS2PRSS3 | |
| SCHEMBL7152748 | 0.81 | F10 (0.63) | F10F7PRSS1PRSS2PRSS3 | |
| SCHEMBL7145184 | 0.80 | F10 (0.54) | F10F7PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474391-A1 | WATER SOLUBLE PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003066588-A1 | WATER SOLUBLE PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-08-14 | — | — | WO | disclosed |