Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 14/20 | 0.66 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.50 |
| ▸ | FECH | P22830 | 1/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
| ▸ | CLK1 | P49759 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | MELK | Q14680 | 1/20 | 0.50 |
| ▸ | MYLK3 | Q32MK0 | 1/20 | 0.50 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.50 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.50 |
| ▸ | TP53RK | Q96S44 | 1/20 | 0.50 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.48 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.48 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918801 | 0.90 | MTOR (0.82) | MTORPIK3CAPIK3CDCSNK2A2FECH | |
| SCHEMBL6874850 | 0.89 | MTOR (0.81) | MTORPIK3CAPIK3CDCSNK2A2FECH | |
| SCHEMBL11885725 | 0.84 | MTOR (0.82) | MTORPIK3CAPIK3CDCSNK2A2FECH | |
| SCHEMBL11887277 | 0.82 | MTOR (0.62) | MTORPIK3CA | |
| SCHEMBL11885735 | 0.81 | MTOR (0.87) | MTORPIK3CAPIK3CDCSNK2A2FECH | |
| SCHEMBL7918798 | 0.79 | MTOR (1.00) | MTORPIK3CAPIK3CDCSNK2A2FECH | |
| SCHEMBL6874822 | 0.79 | MTOR (0.83) | MTORPIK3CAPIK3CDCSNK2A2FECH | |
| SCHEMBL6874961 | 0.78 | MTOR (0.78) | MTORPIK3CAPIK3CDCSNK2A2FECH | |
| SCHEMBL6875573 | 0.75 | MTOR (1.00) | MTORPIK3CAPIK3CDCSNK2A2FECH | |
| SCHEMBL6874948 | 0.75 | MTOR (0.90) | MTORPIK3CAPIK3CDCSNK2A2FECH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011716-A1 | INHIBITORS OF MTOR KINASE AS ANTI-VIRAL AGENTS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2011-01-27 | — | — | WO | disclosed |