Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 13/20 | 0.62 |
| ▸ | TEK | Q02763 | 13/20 | 0.62 |
| ▸ | SRC | P12931 | 10/20 | 0.62 |
| ▸ | KDR | P35968 | 9/20 | 0.57 |
| ▸ | BTK | Q06187 | 6/20 | 0.57 |
| ▸ | FYN | P06241 | 3/20 | 0.57 |
| ▸ | FLT3 | P36888 | 3/20 | 0.57 |
| ▸ | RET | P07949 | 2/20 | 0.57 |
| ▸ | FLT1 | P17948 | 2/20 | 0.57 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.57 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.57 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.57 |
| ▸ | LTK | P29376 | 1/20 | 0.57 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.57 |
| ▸ | CDK8 | P49336 | 1/20 | 0.57 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.57 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.57 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463346 | 0.94 | LCK (0.70) | LCKTEKSRCKDRBTK | |
| SCHEMBL6468048 | 0.90 | LCK (0.76) | LCKTEKSRCKDRBTK | |
| SCHEMBL6465585 | 0.85 | LCK (0.75) | LCKTEKSRCKDRBTK | |
| SCHEMBL6868901 | 0.85 | LCK (0.56) | LCKTEKSRCKDRBTK | |
| SCHEMBL6861341 | 0.81 | LCK (0.60) | LCKTEKSRCKDRBTK | |
| SCHEMBL6462777 | 0.80 | LCK (0.71) | LCKTEKSRCKDRBTK | |
| SCHEMBL6463877 | 0.79 | LCK (0.70) | LCKTEKSRCKDRBTK | |
| SCHEMBL6461479 | 0.79 | LCK (0.67) | LCKTEKSRCKDRBTK | |
| SCHEMBL6461041 | 0.78 | LCK (1.00) | LCKTEKSRCKDRBTK | |
| SCHEMBL6463412 | 0.78 | LCK (0.76) | LCKTEKSRCKDRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004100868-A2 | METHOD OF TREATING TRANSPLANT REJECTION | ABBOTT LABORATORIES (US) | 2004-11-25 | — | — | WO | disclosed |