Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6881616 | 0.88 | GRIN2D (0.38) | EPHX2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6877922 | 0.81 | GRIN2D (0.37) | EPHX2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL14161831 | 0.80 | EPHX2 (0.41) | EPHX2ALOX5EPHX1 | |
| SCHEMBL10820607 | 0.80 | POLB (0.44) | HSD11B1HSD11B2LMNATSHR | |
| SCHEMBL6864625 | 0.79 | GRIN2D (0.53) | EPHX2ALOX5GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1758579 | 0.79 | GRIN2D (0.53) | EPHX2ALOX5GRIN2DGRIN3BGRIN1 | |
| SCHEMBL10756954 | 0.77 | EPHX2 (0.53) | EPHX2ALOX5GRIN2DGRIN3BGRIN1 | |
| SCHEMBL10757410 | 0.77 | EPHX2 (0.53) | EPHX2ALOX5GRIN2DGRIN3BGRIN1 | |
| SCHEMBL9242092 | 0.77 | EPHX2 (0.53) | EPHX2ALOX5GRIN2DGRIN3BGRIN1 | |
| SCHEMBL10760637 | 0.77 | EPHX2 (0.53) | EPHX2ALOX5GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058582-A1 | HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF FUNGAL INFECTIONS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2011-05-19 | — | — | WO | disclosed |