Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 17/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 11/20 | 0.65 |
| ▸ | HTR2B | P41595 | 6/20 | 0.65 |
| ▸ | HRH1 | P35367 | 5/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.65 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877432 | 1.00 | MCHR1 (0.65) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6878425 | 0.88 | MCHR1 (0.72) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6878434 | 0.88 | MCHR1 (0.72) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6873912 | 0.87 | MCHR1 (0.71) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6873917 | 0.87 | MCHR1 (0.71) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6874087 | 0.85 | MCHR1 (0.68) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6879267 | 0.85 | MCHR1 (0.71) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6879271 | 0.85 | MCHR1 (0.71) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| Hydrochloric Acid SCHEMBL6462525 | 0.85 | MCHR1 (0.68) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| Hydrochloric Acid SCHEMBL6462539 | 0.85 | MCHR1 (0.68) | MCHR1ADRA2AHTR2BHRH1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |