Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877666 | 1.00 | MCHR1 (0.53) | MCHR1ADRA2AALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6874715 | 0.90 | MCHR1 (0.53) | MCHR1ADRA2ARAB9AMAPT | |
| SCHEMBL6874706 | 0.90 | MCHR1 (0.53) | MCHR1ADRA2ARAB9AMAPT | |
| SCHEMBL6458632 | 0.88 | MCHR1 (0.52) | MCHR1ADRA2AALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6458637 | 0.88 | MCHR1 (0.52) | MCHR1ADRA2AALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6458281 | 0.87 | MCHR1 (0.59) | MCHR1ADRA2AALDH1A1KMT2AMEN1 | |
| SCHEMBL6458289 | 0.87 | MCHR1 (0.59) | MCHR1ADRA2AALDH1A1KMT2AMEN1 | |
| SCHEMBL27651773 | 0.86 | MCHR1 (0.52) | MCHR1ADRA2AKMT2ARAB9AMAPT | |
| SCHEMBL6875729 | 0.86 | HPGD (0.56) | MCHR1ADRA2AKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL6875723 | 0.86 | HPGD (0.56) | MCHR1ADRA2AKMT2ASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |