Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 12/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877672 | 1.00 | MCHR1 (0.54) | MCHR1ADRA2AADRA1AHTR2BHTR1A | |
| SCHEMBL6876282 | 0.91 | MCHR1 (0.55) | MCHR1ADRA2AADRA1AHTR2BHTR1A | |
| SCHEMBL6876273 | 0.91 | MCHR1 (0.55) | MCHR1ADRA2AADRA1AHTR2BHTR1A | |
| SCHEMBL6458701 | 0.88 | MCHR1 (0.66) | MCHR1ADRA2AADRA1AHTR2BHTR1A | |
| SCHEMBL6458696 | 0.88 | MCHR1 (0.66) | MCHR1ADRA2AADRA1AHTR2BHTR1A | |
| SCHEMBL6877794 | 0.87 | MCHR1 (0.65) | MCHR1ADRA2AADRA1AHTR2BHTR1A | |
| SCHEMBL6875077 | 0.87 | MCHR1 (0.71) | MCHR1ADRA2AADRA1AHTR2BHTR1A | |
| SCHEMBL6875080 | 0.87 | MCHR1 (0.71) | MCHR1ADRA2AADRA1AHTR2BHTR1A | |
| SCHEMBL6877798 | 0.87 | MCHR1 (0.65) | MCHR1ADRA2AADRA1AHTR2BHTR1A | |
| Hydrochloric Acid SCHEMBL6458307 | 0.87 | MCHR1 (0.65) | MCHR1ADRA2AADRA1AHTR2BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |