Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 18/20 | 0.72 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.64 |
| ▸ | HRH1 | P35367 | 4/20 | 0.64 |
| ▸ | HTR2B | P41595 | 4/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877801 | 1.00 | MCHR1 (0.72) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6455678 | 0.91 | MCHR1 (0.78) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6875955 | 0.91 | MCHR1 (0.77) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6455686 | 0.91 | MCHR1 (0.78) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6875948 | 0.91 | MCHR1 (0.77) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| Hydrochloric Acid SCHEMBL6463336 | 0.90 | MCHR1 (0.76) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| Hydrochloric Acid SCHEMBL6463339 | 0.90 | MCHR1 (0.76) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6464945 | 0.88 | MCHR1 (0.82) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6464940 | 0.88 | MCHR1 (0.82) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6875866 | 0.87 | MCHR1 (0.69) | MCHR1ADRA2AADRA1AHRH1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |