SCHEMBL6877863

SCHEMBL6877863

O=C(O)C1CC=NO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30536123 0.98
SCHEMBL7168808 0.77
SCHEMBL76303 0.64 SUCNR1 (0.44)
SCHEMBL25662212 0.64 SUCNR1 (0.44)
SCHEMBL25661131 0.64 SUCNR1 (0.44)
SCHEMBL25661135 0.64 SUCNR1 (0.44)
SCHEMBL11412447 0.64
SCHEMBL11459808 0.60 SMN1; SMN2 (0.35)
SCHEMBL25661144 0.60 GABRR1 (0.36)
SCHEMBL25661145 0.60 GABRR1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024110366-A1 A METHOD FOR CONTROLLING WEEDS SYNGENTA CROP PROTECTION AG (CH) 2024-05-30 WO claimed
CN-112920005-B Preparation method of (R) -3- (3-chloro-2-fluorobenzene) -4, 5-dihydroisoxazole-5-carboxylic acid 上海李氏化学科技有限公司 2022-06-14 CN claimed
US-12570675-B2 Boronic acid compounds LG CHEM, LTD. (KR) 2026-03-10 US disclosed
WO-2025108865-A1 HERBICIDAL COMPOSITIONS BAYER AKTIENGESELLSCHAFT (DE) 2025-05-30 WO disclosed
CN-118843613-A RXFP1 agonists 百时美施贵宝公司 2024-10-25 CN disclosed
EP-4441035-A1 PROCESS FOR PRODUCING ISOXAZOLINE-5,5-VINYLCARBOXYLIC ACID DERIVATIVES Bayer Aktiengesellschaft (DE) 2024-10-09 EP disclosed
EP-4422746-A1 RXFP1 AGONISTS Bristol-Myers Squibb Company (US) 2024-09-04 EP disclosed
US-20240101579-A1 BORONIC ACID COMPOUNDS LG CHEM, LTD. (KR) 2024-03-28 US disclosed
CN-117616014-A Process for preparing isoxazoline carboxylic acid derivatives 拜耳公司 2024-02-27 CN disclosed
CN-111655686-B Tetrahydroisoquinoline derivative and preparation method and application thereof 四川科伦博泰生物医药股份有限公司 2024-02-09 CN disclosed
WO-2024013016-A1 HERBICIDAL COMPOSITIONS BAYER AKTIENGESELLSCHAFT (DE) 2024-01-18 WO disclosed
WO-2010036000-A2 NOVEL OXAZOLIDINONE DERIVATIVES WITH CYCLIC AMIDOXIME OR CYCLIC AMIDRAZONE AND PHARMACEUTICAL COMPOSITIONS THEREOF LEGOCHEM BIOSCIENCE LTD. (KR) 2010-04-01 WO disclosed
WO-2010008775-A1 AMINOPYRIDOPYRAZINONE DERIVATIVES FOR TREATING NEURODEGENERATIVE DISEASES LIGAND PHARMACEUTICALS INC. (US) 2010-01-21 WO disclosed
WO-2002000651-A2 FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2002-01-03 WO disclosed
WO-2000033836-A9 5-MEMBERED HETEROCYCLES FOR THE TREATMENT OF HUMAN DISEASES INVOLVING MODULATORS OF SELECTINS ONTOGEN CORP (US) 2001-10-04 WO disclosed
CN-1251095-A Lipase capalyzed dynamic resolution of isoxazoline thioester to isoxazoline carboxylic acids PONT PHARMACEUTICAL CO DU (US) 2000-04-19 CN disclosed
US-6022977-A Dynamic resolution of isoxazoline thioesters to isoxazoline carboxylic acids DUPONT PHARMACEUTICALS COMPANY (US) 2000-02-08 US disclosed
EP-0971906-A1 LIPASE CATALYZED DYNAMIC RESOLUTION OF ISOXAZOLINE THIOESTERS TO ISOXAZOLINE CARBOXYLIC ACIDS Du Pont Pharmaceuticals Company (US) 2000-01-19 EP disclosed
WO-1998042687-A1 LIPASE CATALYZED DYNAMIC RESOLUTION OF ISOXAZOLINE THIOESTERS TO ISOXAZOLINE CARBOXYLIC ACIDS DU PONT PHARMACEUTICALS COMPANY (US) 1998-10-01 WO disclosed
WO-1996037492-A1 ISOXAZOLINE AND ISOXAZOLE DERIVATIVES AS INTEGRIN RECEPTOR ANTAGONISTS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-11-28 WO disclosed