⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28358258 | 0.77 | — | — | |
| SCHEMBL27447755 | 0.77 | — | — | |
| SCHEMBL28675088 | 0.76 | — | — | |
| SCHEMBL18594211 | 0.74 | — | — | |
| SCHEMBL27397027 | 0.74 | — | — | |
| SCHEMBL21305084 | 0.72 | — | — | |
| SCHEMBL24659058 | 0.70 | — | — | |
| SCHEMBL29282296 | 0.70 | — | — | |
| SCHEMBL23790575 | 0.70 | — | — | |
| SCHEMBL21362271 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116802184-A | Pyrazolothiazole carboxamides and their use as PDGFR inhibitors | 埃科特莱茵药品有限公司 | 2023-09-22 | — | — | CN | disclosed |
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| CN-108440507-A | Compound as apoptosis protein inhibitor and its application | 南京圣和药业股份有限公司 | 2018-08-24 | — | — | CN | disclosed |
| CN-108137600-A | Condensed pyrazole derivatives as kinase inhibitor | UCB生物制药私人有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-108137532-A | PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV保健英国第五有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-104311477-A | Nitrogen-containing heterocyclic ring compound and application thereof | UNIV EAST CHINA SCIENCE & TECH | 2015-01-28 | — | — | CN | disclosed |
| WO-2011137109-A1 | AZAINDAZOLE AMIDE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-11-03 | — | — | WO | disclosed |
| WO-2011109470-A1 | HETEROARYL NITRILE COMPOUNDS USEFUL AS INHIBITORS OF CATHEPSIN-S | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-09-09 | — | — | WO | disclosed |
| CN-1135252-C | Hindered amine compound, resin composition, polyurethane fibre, process for preparing polyurethane fibre, and elastic braided fabric | ����ļ���ʽ���� | 2004-01-21 | — | — | CN | disclosed |
| CN-1257888-A | Hindered amine compound, resin composition, polyurethane fibre, process for preparing polyurethane fibre, and elastic braided fabric | TOYO BOSEKI (JP) | 2000-06-28 | — | — | CN | disclosed |