Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | CCND1 | P24385 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6878155 | 1.00 | MCHR1 (0.46) | MCHR1HTR7ADRA2ANPY5RHCRTR2 | |
| SCHEMBL6877198 | 0.89 | USP2 (0.48) | MCHR1HTR7HCRTR2CDK1CDK4 | |
| SCHEMBL6877203 | 0.89 | USP2 (0.48) | MCHR1HTR7HCRTR2CDK1CDK4 | |
| SCHEMBL6875684 | 0.87 | MCHR1 (0.51) | MCHR1HTR7ADRA2ANPY5RCDK1 | |
| SCHEMBL6875679 | 0.87 | MCHR1 (0.51) | MCHR1HTR7ADRA2ANPY5RCDK1 | |
| SCHEMBL6880535 | 0.86 | MCHR1 (0.48) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6869215 | 0.86 | MCHR1 (0.48) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6880528 | 0.86 | MCHR1 (0.48) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6869211 | 0.86 | MCHR1 (0.48) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6878345 | 0.83 | MCHR1 (0.49) | MCHR1ADRA2ANPY5RADRA1AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |